Film, penned by Lough, is the first in a planned franchise and is a sexploitation-serial-killer-slasher-road-movie circa 1989.

Lough ("Bomb the System") reckons "Splatter Sisters" could create a subgenre, which he calls "Skinemax Cinema," based on the direct-to-cable movies of his childhood.

Green ("Pineapple Express," "Your Highness") said while Lough's film is inspired by the horror classics of the 1980s, it has a fresh spin that raises the bar.

"This is a role Marilyn Manson was born to play, and with Evan Rachel Wood bringing dramatic gravity to the ensemble, I have no doubt this will take the horror genre to a new level," Green said.

"Splatter Sisters" was announced in Cannes. Pressman is at the fest for the world preem of 20th Century Fox's "Wall Street: Money Never Sleeps." He is one of the producers of helmer Oliver Stone's sequel.

"Lough's unique talent and energy will make 'Splatter Sisters' a very special and markedly commercial film," Pressman said. "I've always been attracted to smart movies about killers made by directors with a real vision,"

Wood last starred on the bigscreen in Woody Allen's "Whatever Works," which was released in 2009. -variety.com